OUR PAPERS

We are a team of scientists, engineers, and clinicians working together to cure cancer.

An immune-based tool platform for in vivo cell clearance.

Zhang J, Tsukui T, Wu X, Brito A, Trumble JM, Caraballo JC, Allen GM, Zavala-Solorio J, Zhang C, Paw J, Lim WA, Geng J, Kutskova Y, Freund A, Kolumam G, Sheppard D, Cohen RL

Life Science Alliance (2023). doi: 10.26508/lsa.202201869.

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Synthetic cytokine circuits that drive T cells into immune-excluded tumors.

Greg M. Allen, Nick W. Frankel, Nish R. Reddy, Hersh K. Bhargava, Maia A. Yoshida, Sierra R. Stark, Megan Purl, Jungmin Lee, Jacqueline L. Yee, Wei Yu, Aileen W. Li, K. Christopher Garcia, Hana El-Samad, Kole T. Roybal, Matthew H. Spitzer, Wendell A. Lim

Science (2022). doi: 10.1126/science.aba1624.

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Media & Press


Precise T cell recognition programs designed by transcriptionally linking multiple receptors.

Williams JZ, Allen GM, Shah D, Sterin IS, Kim KH, Garcia VP, Shavey GE, Yu W, Puig-Saus C, Tsoi J, Ribas A, Roybal KT, Lim WA

Science (2020). doi: 10.1126/science.abc6270.

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Cell Mechanics at the Rear Act to Steer the Direction of Cell Migration.

Allen GM, Lee KC, Barnhart EL, Tsuchida MA, Wilson CA, Gutierrez E, Groisman A, Theriot JA, Mogilner A

Cell Systems (2020). doi: 10.1016/j.cels.2020.08.008.

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Myosin II contributes to cell-scale actin network treadmilling through network disassembly.

Wilson CA, Tsuchida MA, Allen GM, Barnhart EL, Applegate KT, Yam PT, Ji L, Keren K, Danuser G, Theriot JA

Nature (2010). doi: 10.1038/nature08994.

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Bipedal locomotion in crawling cells.

Barnhart EL, Allen GM, Jülicher F, Theriot JA

Biophysical Journal (2010). doi: 10.1016/j.bpj.2009.10.058.

Journal Website | PubMed


Mechanism of shape determination in motile cells.

Keren K, Pincus Z, Allen GM, Barnhart EL, Marriott G, Mogilner A, Theriot JA

Nature (2008). doi: 10.1038/nature06952.

Journal Website | PubMed